COVID-19 continues to change, and so do its variants. The XFG variant, more commonly known as Stratus, is the latest COVID-19 virus mutation gaining momentum.
As respiratory illness season kicks into full gear, knowing the facts about the COVID-19 variant Stratus will help you protect yourself and your family with confidence. Here’s a quick guide for what you need to know.
What is COVID-19 Stratus?
Stratus is a newer form of the COVID-19 virus that was first detected in January 2025 in Southeast Asia. By June, the variant had spread to 38 countries, leading the World Health Organization (WHO) to designate Stratus as a “SARS-CoV-2 variant under monitoring.” WHO is watching the variant carefully to learn more about how it acts and what it might mean for our health.
How is Stratus Different than Other COVID Variants Like Nimbus
In the U.S., COVID-19 cases have been on the rise throughout the summer, according to the Center for Disease Control (CDC). News reports have linked two recent variants, Nimbus (NB.1.8.1) and Stratus as the causes.
Nimbus is highly infectious due to its strong ability to bind to human cells and is sometimes linked to a severe “razor blade” sore throat.
Stratus exhibits “marginal additional immune evasion” over Nimbus, according to the WHO. Meaning, that this latest variant has developed a slightly better ability to avoid being recognized and attacked by the immune system. This could make it harder for the body to fight off the virus, especially if someone hasn’t been vaccinated or previously infected. However, as the word “marginal” suggests, this change is small and should not be a major concern for most people.
Common Symptoms of Stratus
Most cases of COVID-19 variant Stratus are mild, particularly if you’re vaccinated or have received a booster. However, knowing what to watch for can empower you to take the right steps for your health.
Many symptoms of the 2025 Stratus mutation are like previous versions of COVID-19. The most frequent symptoms include:
- Persistent, dry cough
- Tiredness or fatigue
- Fever
Some people may also notice:
- Shortness of breath
- Chest tightness
- Sore or scratchy throat
- Headaches and body aches
- Upset stomach, nausea, or loss of appetite
- Loss of taste or smell (now less common)
- Brain fog or trouble concentrating
If you experience these symptoms, support and treatments are available. It’s important to monitor how you feel and reach out to your healthcare provider with any concerns.
7 Prevention Tips
You can lower your risk of catching or spreading COVID-19 variant Stratus by following a few key steps:
- Get vaccinated and stay up to date with booster shots.
- Wear a mask—especially in crowded or indoor places. Masks like N95 or KN95 provide good protection.
- Open a window or use an air filter to keep fresh air moving indoors.
- Wash your hands often with soap and water for at least 20 seconds.
- Avoid close contact in indoor spaces that don’t have good airflow.
- If you or someone you live with is at higher risk, consider extra precautions.
- Think carefully before you travel. Check local COVID-19 levels and bring a mask and hand sanitizer.
Treatment Steps
If you become ill with COVID Stratus, there are effective treatments available to help you feel better and lower your risk of complications. Many people manage their symptoms comfortably at home with a combination of medical care and self-care.
- Antiviral medications such as Paxlovid may be prescribed by your doctor and can reduce the risk of serious illness, especially for those at higher risk.
- Getting plenty of rest and staying well hydrated helps your body recover.
- Over-the-counter medicines like acetaminophen or ibuprofen can help reduce fever, body aches or headaches.
- Isolating for at least five days after your symptoms begin is important to protect those around you.
- Keep track of your symptoms. Using a home oxygen monitor, if you have one, can give you peace of mind by ensuring your oxygen levels stay safely above 95 percent.
When to See a Doctor for COVID-19
While most people with COVID-19 can recover safely at home, there are times when seeking medical care is important.
When to contact your doctor:
- A high fever (over 103°F) lasting more than three days, even with medication.
- Symptoms that suddenly get worse after initially improving.
For children under 2 years old, see a doctor if you notice irritability, fast breathing or not wanting to drink their bottle/breastfeed.
When to go to the emergency room:
- Chest pain, ongoing tightness, or pressure that does not go away.
- Feeling very dizzy, confused, or having trouble staying awake.
- Signs of severe dehydration, like a very dry mouth, producing little or no urine, or fainting spells.
- Difficulty breathing that feels severe or is getting worse.
- Oxygen levels that stay below 95 percent, especially if you check with a home oxygen monitor.
If you are over 65, have existing health conditions like diabetes or heart disease, or have a weakened immune system, it’s a good idea to reach out to your doctor early—even if your symptoms appear mild. A quick phone call for advice can offer reassurance and early support.
