Stony Brook Medicine Health News
A husband and wife looking over the best prostate cancer treatments available in early stages.

Best Treatment for Prostate Cancer in Early Stages

After a prostate cancer diagnosis, it’s important to understand your treatment options. Learning about the fundamentals of prostate cancer, from diagnosis to treatment, will empower you to make informed decisions with your healthcare team.

Understanding Prostate Cancer

Prostate cancer is a type of cancer that begins in the prostate gland, a small walnut-shaped gland located in men below the bladder and in front of the rectum. 

Throughout a man’s lifetime, some prostate cells may become cancerous. Early-stage prostate cancer is present only in the prostate and has not grown to other body parts. If left untreated, these cancerous cells can spread beyond the prostate gland to areas such as the lymph nodes and bones. Early detection and treatment are crucial for managing prostate cancer effectively.

Diagnosis of Early-Stage Prostate Cancer

Most prostate cancers in the United States are identified through a prostate-specific antigen (PSA) screeningor digital rectal examination, which are typically done during an annual physical with your primary care doctor or urologist.

PSA is a protein in the blood produced by prostate cells, which can be measured with a simple blood test. Elevated PSA isn’t always caused by prostate cancer; benign conditions like an infection and urinary retention can also alter these protein levels. While the PSA test is not foolproof for prostate cancer detection, it is currently the most commonly used tool for identifying cancer early on. 

Other tests used to diagnosis prostate cancer include a PCA3 urine test and 4Kscore blood test, both of which help differentiate prostate cancer from other causes of elevated PSA. 

Your urologist may decide to proceed with a biopsy depending on several factors, including the PSA level, nature of the prostate during examination, family history of cancer, age, race and other medical comorbidities. Biopsies should be performed only after discussing the risks and benefits with a urologist. 

Treatment Options for Early-Stage Prostate Cancer

If you are diagnosed with prostate cancer, deciding on which therapy to select can be a confusing process. The choice of treatment depends on various factors such as the aggressiveness of the cancer, the patient’s age and overall health, and personal preferences. Each treatment has its risks, benefits and impact on quality of life. 

You don’t have to make treatment decisions by yourself. Your urologist and healthcare team will guide you through the options and help you make the best decision for your individualized case.

The most common treatment options for prostate cancer in early stages include: 

1. Active Surveillance

Active surveillance is a way to monitor low-risk prostate cancer with a plan of timely intervention should the tumor become larger or grow in size. Patients undergo regular monitoring and testing to track the progression of the cancer without immediate treatment.

2. Radical Prostatectomy

A radical prostatectomy is surgery to remove the entire prostate gland and seminal vesicles. Sometimes, the regional lymph nodes are also removed. A modern, minimally invasive approach to prostatectomy surgery is the use of a robotic-assisted surgical system, which the surgeon operates. This results in less blood loss, shorter hospital stays and a quicker recovery. 

3. Radiation Therapy

Radiation can be given as external beam radiation therapy (EBRT) and as brachytherapy. EBRT is external and local radiation treatment that is done with a machine. Brachytherapy radiation is given from inside the body, with radioactive seeds placed permanently in the prostate or with narrow, seed-filled tubes that are placed temporarily for one or two days.

4. Cryotherapy

Cryotherapy is used to treat localized (no cancer beyond the prostate gland) prostate cancer, killing cancer cells in the prostate by freezing them. This procedure is mainly used when radiation therapy has been ineffective. 

5. Hormone Therapy

Hormone therapy for prostate cancer aims to reduce levels of male hormones, particularly testosterone, in the body. Hormone therapy may involve medications or surgical procedures to suppress testosterone production or block its effects on cancer cells. It is commonly used in combination with other treatments for prostate cancer, such as surgery or radiation therapy.

Choosing the Best Treatment Option

Choosing the best treatment option for early-stage prostate cancer involves a collaborative effort between the patient and their healthcare team, which may include a urologist, oncologist, radiation oncologist and other specialists. 

Common factors to consider include the:

  • Stage and grade of the cancer
  • Patient’s lifestyle and preferences
  • Potential benefits and risks of each treatment option
  • Likelihood of the cancer responding to treatment

Ultimately, the best treatment option for a patient’s individual needs should be based on a thorough discussion of these factors.

Stony Brook Cancer Center offers a full spectrum of prostate cancer care, including advanced diagnostics and treatment from a multidisciplinary team of experts. Find out more about prostate cancer treatment here.

Stony Brook’s Urological Oncology team serves the community with new technological advancements that assist in both diagnosis and treatment. Find out more about Stony Brook Urology here.

  • Michael Hung, MD
    Urologic Oncology
    Clinical Assistant Professor in Urology

    Dr. Hung is dedicated to providing exceptional patient-centered care and fostering an environment of open communication for patients to take an active role in their health. He believes in the importance of a collaborative approach to medicine and works closely with our comprehensive multidisciplinary teams. Dr. Hung specializes in the management of complex urologic cancers. He earned his medical degree from Albert Einstein College of Medicine and went on to complete his urology residency at Stony Brook University Hospital. He completed a Society of Urologic Oncology (SUO) fellowship at New York-Presbyterian Weill Cornell Medicine. His training in robotic surgery enables him to treat complex urologic conditions using minimally invasive approaches. He has published numerous peer-reviewed articles and has expertise in treating all cancers of the genitourinary tract, including cancers of the prostate, bladder, kidney, ureter, and testis.

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  • Wayne Waltzer, MD
    Urologic Oncology
    Kidney Transplant Surgery
    Urology

    Dr. Wayne Waltzer is a board-certified urologist specializing in renal transplantation and urologic oncology. He is a professor and chairman of the Department of Urology and the Director of Renal Transplant at Stony Brook University Hospital. In addition, Dr. Waltzer is a member of the Society of Urologic Oncology and the American Society of Transplant Surgeons. He completed his Residency training at the University of Pittsburgh and Fellowship training in kidney transplant surgery at the Mayo Clinic. He participated in the first kidney transplant performed on Long Island at Stony Brook in 1982. Dr. Waltzer pursued a career in urology and renal transplantation to have the opportunity to treat patients with a wide variety of complex urological disorders and kidney diseases. He currently performs renal transplants and treats conditions such as kidney cancer, ureteral cancer, bladder cancer, testicular cancer, and prostate cancer. Additionally, he manages complex cases requiring reconstructive surgery of the urinary tract. As part of his armamentarium, he uses advanced techniques such as the DaVinci robot to perform such surgeries.

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This article is intended to be general and/or educational in nature. Always consult your healthcare professional for help, diagnosis, guidance and treatment.